Malaria RDT which produced by several companies today use different method one another and that may affect in its diagnostic values. Therefore, the study of diagnostic value each RDTs is needed in order to find the best RDTs used in clinical practice. Objective: to determine diagnostic values of malaria RDT (sensitivity, specificity, positif predictive value/PPV, and negative predictive value/NPV) of malaria RDT using antigenic target of P.falciparum specific Histidine rich protein (HRP-2) and pLDH (Pan and PvpLDH). It is a cross sectional study and the samples were collected during February 2008 to September 2009 in several hospitals in Malang. The gold standard diagnostic for malaria is blood smear. Mc Nemar test is used to determine sensitivity, spesificity, PPV, and NPV. Result: 77 samples were obtained (47 malaria cases and 30 controls) and we found that the sensitivity, specificity, PPV and NPV of HRP-2 were 94,1%; 100%; 100%; 96,7% consecutively and those for PvpLDH were 94,7%; 100; 100%; 96,7%. Conclusion: RDT using HRP-2 and PvpLDH have a good diagnostic value and considered as alternative diagnostic of malaria.
Silakan klik di sini untuk bahasa indonesia
Tidak ada komentar:
Posting Komentar
silakan komentar di sini